313-06-4
- Product Name：Estra-1,3,5(10)-triene-3,17-diol(17b)-, 17-cyclopentanepropanoate
- Molecular Formula：C26H36O3
- Purity：99%
- Molecular Weight：
Product Details;
CasNo： 313-06-4
Molecular Formula： C26H36O3
Appearance： white or off-white crystalline powder
|
313-06-4 Name |
|
|
Name |
Estra-1,3,5(10)-triene-3,17-diol(17b)-, 17-cyclopentanepropanoate |
|
Synonym |
Estradiol Cypionate;(17b)-estra-1,3,5(10)-triene-3,17-diol17-cyclopentanepropanoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 17beta-cyclopentanepropanoate;17beta-Estradiol 17-cyclopentylpropionate;17beta-Estradiol cyclopentanepropionate;17beta-Estradiol cypionate;3-cyclopentylpropanoic acid [(13S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] ester;3,5(10)-triene-3,17-diol(17-beta)-estra-17-cyclopentanepropanoate;3,5(10)-triene-3,17-diol(17beta)-estra-17-cyclopentanepropanoate |
|
313-06-4 Biological Activity |
|
|
Description |
Estradiol cypionate is a 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptorIC50 value:Target: estrogen receptorEstradiol cypionate is a synthetic ester, is a estrogen. Compared to other commonly used estradiol esters, via the intramuscular route, Estradiol cypionate is found to have the longest duration of action with a duration of ~11 days |
|
Related Catalog |
Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology |
|
References |
[1]. Feng X, et al. NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. Cell Death Dis. 2017 May 11;8(5):e2783. |
|
313-06-4 Chemical & Physical Properties |
|
|
Melting point |
≥300 °C(lit.) |
|
Boiling point |
532.8±50.0 °C at 760 mmHg |
|
Density |
1.2±0.1 g/cm3 |
|
Molecular Formula |
C26H36O3 |
|
Molecular Weight |
396.562 |
|
Flash Point |
207.7±22.9 °C |
|
PSA |
46.53000 |
|
LogP |
7.59 |
|
Exact Mass |
396.266449 |
|
Vapour Pressure |
0.0±1.5 mmHg at 25°C |
|
Index of Refraction |
1.579 |
|
313-06-4 Description |
|
Estradiol cypionate is a White to Off-White Solid. It is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). The solubility of estradiol cypionate in ethanol is approximately 20 mg/ml and approximately 15 mg/ml in DMSO and DMF. |
|
313-06-4 Uses |
|
Estradiol Cypionate is the cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol Cypionate is present in injectable contraceptive formulations. Used in hormone replacement therapy with potential for improving cognition in post-menopausal women. |
Relevant Products
-
4-Hydroxyphenethyl alcoholCAS NO.: 501-94-0CAS：501-94-0
-
BETA-NICOTINAMIDE MONONUCLEOTIDECAS：1094-61-7
-
trans-Ferulic acidCAS：537-98-4
