88-58-4
- Product Name：2,5-Di-tert-butylhydroquinone
- Molecular Formula：C14H22O2
- Purity：99%
- Molecular Weight：
Product Details;
CasNo： 88-58-4
Molecular Formula： C14H22O2
Appearance： White or light yellow crystals
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88-58-4 Name |
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Name |
2,5-Di-tert-butylhydroquinone |
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Synonym |
BHQ;DBHQ;Dibutylhydroquinone;DI-TERT-BUTYL HYDROQUINONE(2,5-);DI-T-BUTYLHYDROQUINONE;2,5-Di-tert-butylquinol;Di-Tertiary Butylhydroquinone;2,5-DI-TERT-BUTYL-1,4-HYDROQUINONE (DBHQ) |
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88-58-4 Biological Activity |
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Description |
2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1]. |
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Related Catalog |
Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase Signaling Pathways >> Immunology/Inflammation >> COX |
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Target |
5-LO:1.8 μM (IC50) COX-2:14.1 μM (IC50) |
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In Vitro |
DTBHQ influences arachidonic acid (AA) metabolism in biologically relevant concentrations in vitro[1]. |
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References |
[1]. Zsofia Kutil, et al. The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro. Food and Agricultural Immunology. Volume 26, 2015-Issue 4. |
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88-58-4 Chemical & Physical Properties |
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Melting point |
216-218 °C(lit.) |
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Boiling point |
334.4±37.0 °C at 760 mmHg |
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Density |
1.0±0.1 g/cm3 |
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Molecular Formula |
C14H22O2 |
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Molecular Weight |
222.323 |
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Flash Point |
151.5±21.1 °C |
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PSA |
40.46000 |
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LogP |
4.02 |
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Exact Mass |
222.161987 |
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Vapour Pressure |
0.0±0.8 mmHg at 25°C |
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Index of Refraction |
1.520 |
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Storage condition |
Store at RT |
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Stability |
Stable. Incompatible with oxidizing agents. |
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88-58-4 Description |
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Mobilizes Ca2+ specifically from the Ins(1,4,5)P3-sensitive Ca2+ stores by inhibiting microsomal and sarcoplasmic reticulum Ca2+-ATPase activity. Does not affect mitochondrial Ca2+ fluxes or plasma membrane Ca2+/Mg2+ ATPase activity. Useful for the study of endomembrane Ca2+ stores and plasma membrane Ca2+ permeability pathways. |
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88-58-4 Uses |
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2,5-Di-tert-butylhydroquinone is the oxidation substrate used to measure the catalytic activity of the copper(II) enzyme-like catalysts. |
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