Product classification

130-85-8

Product Name：Pamoic acid
Molecular Formula：C₂₃H₁₆O₆
Purity：99%
Molecular Weight：

Inquiry

Product Details;

CasNo： 130-85-8

Molecular Formula： C₂₃H₁₆O₆

Appearance： Fine Yellow Powder

130-85-8 Properties

Molecular Formula:C23H16O6
Molecular Weight:388.376
Appearance/Colour:Fine Yellow Powder
Vapor Pressure:2.13E-17mmHg at 25°C
Melting Point:≥300ºC (dec.)
Refractive Index:1.4593 (estimate)
Boiling Point:642.7 ºC at 760 mmHg
PKA:2.67±0.30(Predicted)
Flash Point:356.5ºC
PSA：115.06000
Density:1.499 g/cm³
LogP:4.39140

130-85-8 Usage

Chemical Properties

Pamoic acid is yellow to yellow-green crystalline powder

Uses

Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases.

Uses

Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Safety Profile

Poison by intraperitoneal route. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

InChI:InChI=1/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)/p-2

130-85-8 Relevant articles

Synthesis of dihomocalix[4]naphthalenes: First members of a new class of [1.2.1.2](1,3)naphthalenophanes

Georghiou, Paris E.,Li, Zhaopeng,Ashram, Muhammad,Miller, David O.

, p. 3865 - 3869 (1996)

TREATMENT OF DISORDERS ASSOCIATED WITH G PROTEIN-COUPLED RECEPTOR 35 (GPR35)

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Page/Page column 18, (2011/02/24)

Compounds are provided having agonistic activity against G protein- coupled receptor 35 (GPR35). The compounds are useful for providing antinociception, providing neuroprotection in case of stroke or ischemia, or treating gastric inflammation.

ALKYLENEBISNAPHTOL DERIVATIVES AND CHARGE CONTROL AGENT COMPRISING THE SAME

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Page 9-10, (2008/06/13)

The present invention provides an alkylenebisnaphthol derivative represented by formula [I]: and a salt thereof. The compound of the present invention has an excellent triboelectric charge property and useful as charge control agent for electrophotographic toners.

Crystalline cepham acid addition salts and processes for their preparation

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, (2008/06/13)

Novel crystalline cephem acid addition salts and processes for their preparation Compounds of the formula I STR1 in which n is equal to 1 or 2 and m is 0.4-2.6, and where X is the anion of a carboxylic acid, have antibacterial activity.