Product Details;
CasNo： 81-13-0
Molecular Formula： C9H19NO4
Appearance： clear colorless to slightly yellow viscous liquid
|
81-13-0 Name |
|
|
Name |
Dexpanthenol |
|
Synonym |
4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(theta)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-d-(+)-butyramid;Alcopan-250;Bepanthen;Bepanthene;Bepantol;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)- |
|
81-13-0 Biological Activity |
|
|
Description |
D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. |
|
Related Catalog |
Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology |
|
References |
[1]. Oguz A, et al. Topical N-acetylcysteine improves wound healing comparable to dexpanthenol: an experimental study. Int Surg. 2015 Apr;100(4):656-61. |
|
81-13-0 Chemical & Physical Properties |
|
|
Melting point |
64～69°C |
|
Boiling point |
483.6±45.0 °C at 760 mmHg |
|
Density |
1.2±0.1 g/cm3 |
|
Molecular Formula |
C9H19NO4 |
|
Molecular Weight |
205.251 |
|
Flash Point |
246.3±28.7 °C |
|
PSA |
89.79000 |
|
LogP |
-0.92 |
|
Exact Mass |
205.131409 |
|
Vapour Pressure |
0.0±2.8 mmHg at 25°C |
|
Index of Refraction |
1.502 |
|
81-13-0 Description |
|
Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine. |
|
81-13-0 Uses |
|
Relevant Products
-
-
3,5-Dimethoxy-4-hydroxybenzaldehydeCAS：134-96-3
-
Toluene ethylsulfonamideCAS：8047-99-2
