2316-26-9
- Product Name：3,4-Dimethoxycinnamic acid
- Molecular Formula：C11H12O4
- Purity：99%
- Molecular Weight：
Product Details;
CasNo： 2316-26-9
Molecular Formula： C11H12O4
Appearance： Slightly yellow to light beige powder
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2316-26-9 Name |
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Name |
3,4-Dimethoxycinnamic acid |
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Synonym |
RARECHEM BK HC T253;TIMTEC-BB SBB005722;OTAVA-BB BB0107620014;(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoic acid;3,4-Dimethoxycinnamic acid 98%;Caffeic acid dimethyl ether;3,4-DIMETHOXYCINNAMIC ACID 99% PREDOMINANTLY TRANS ISOMER;3,4-DiMethoxycinnaMic acid, 99% 5GR |
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2316-26-9 Biological Activity |
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Description |
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects |
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Related Catalog |
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Research Areas >> Cancer Research Areas >> Infection Natural Products >> Phenylpropanoids |
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In Vitro |
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1]. 3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner. |
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References |
[1]. Li L, et al. Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signalingpathway. Int J Oncol. 2018 Jul;53(1):225-236. |
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2316-26-9 Chemical & Physical Properties |
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Melting point |
181-183 °C(lit.) |
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Boiling point |
367.4±27.0 °C at 760 mmHg |
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Density |
1.2±0.1 g/cm3 |
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Molecular Formula |
C11H12O4 |
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Molecular Weight |
208.211 |
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Flash Point |
144.0±17.2 °C |
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PSA |
55.76000 |
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LogP |
2.24 |
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Exact Mass |
208.073563 |
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Vapour Pressure |
0.0±0.9 mmHg at 25°C |
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Index of Refraction |
1.574 |
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Storage condition |
-20°C |
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2316-26-9 Uses |
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3,4-Dimethoxycinnamic Acid is a Cinnamic Acid (C442030) derivative,used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids. |
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