127464-43-1
- Product Name：Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1)
- Molecular Formula：C8H11NO.C4H6O4
- Purity：99%
- Molecular Weight：
Product Details;
CasNo： 127464-43-1
Molecular Formula： C8H11NO.C4H6O4
Butanedioic acid 2-ethyl-6-methyl-3-pyridinol (1:1) 127464-43-1 In Medicine, In Stock
- Molecular Formula:C8H11NO.C4H6O4
- Molecular Weight:255.27
- Vapor Pressure:0.0022mmHg at 25°C
- Melting Point:119-120 °C
- Boiling Point:280.6 °C at 760 mmHg
- Flash Point:123.5 °C
- PSA：107.72000
- LogP:1.59380
127464-43-1 Usage
Uses
The Chinese name of Mesidol is 2-ethyl-6methyl-3-hydroxypyridine succinic acid (Mexidox), 2-ethyl-6-methyl-3-hydroxypyridine succinate (emoxypine, product Name-MEXIDOL?, etc.) is widely used in medicine as an antioxidant and anti-hypoxic agent. Use 2-ethyl-6-methyl-3-hydroxypyridine succinate as a nootropic and anxiolytic, anti-ischemic and atherosclerotic, anti-angina, liver protection, antibacterial, etc.
Preparation
3.5 liters of ethanol, 1.2 kg of 2-ethyl-6-methyl-3-hydroxypyridine and 1.0 kg of succinic acid were added to the reactor. The reaction mass is heated to the boiling point of ethanol (78°C) and stirring is continued for 20 minutes until the components are completely dissolved. Then, keep the reaction mass in the reactor under stirring until the temperature reaches 20°C, cool to 5°C and keep at this temperature for 16 hours, stirring occasionally. The suspension is then stirred until the material is homogeneous, overloaded in a centrifuge and filtered. The precipitate of the succinate salt of 2-ethyl-6-methyl-3-hydroxypyridine was dried to constant weight in a vacuum oven at 45°C. The yield of the target product 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexitrad) was 89%.
InChI:InChI=1/C8H11NO.C4H6O4/c1-3-7-8(10)5-4-6(2)9-7;5-3(6)1-2-4(7)8/h4-5,10H,3H2,1-2H3;1-2H2,(H,5,6)(H,7,8)
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