Product Details;
CasNo: 130-85-8
Molecular Formula: C23H16O6
Appearance: Fine Yellow Powder
Pamoic acid 130-85-8 Powder Supplier
- Molecular Formula:C23H16O6
- Molecular Weight:388.376
- Appearance/Colour:Fine Yellow Powder
- Vapor Pressure:2.13E-17mmHg at 25°C
- Melting Point:≥300ºC (dec.)
- Refractive Index:1.4593 (estimate)
- Boiling Point:642.7 ºC at 760 mmHg
- PKA:2.67±0.30(Predicted)
- Flash Point:356.5ºC
- PSA:115.06000
- Density:1.499 g/cm3
- LogP:4.39140
API Pamoic acid 130-85-8 Powder Usage
130-85-8 Uses |
Pamoic acid is Fine Yellow Powder, while it's Molecular Formula is C23H16O6. Pamoic acid (PAM), a solubilizer commonly used in drug formulations and which is not absorbed across mucosae and by the oral route (Neubig 2010; Zhao et al. 2010). |
InChI:InChI=1/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)/p-2
130-85-8 Relevant articles
Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia
Federica De Leo, Alice Rossi, Francesco De Marchis, Cristina Cigana, Medede Melessike, Giacomo Quilici, Ida De Fino, Malisa Vittoria Mantonico, Chantal Fabris, Alessandra Bragonzi, Marco Emilio Bianchi & Giovanna Musco
Molecular Medicine volume 28, Article number: 108 (2022)
To address pharmacological inhibition of HMGB1 with small molecules, we explored the therapeutic potential of pamoic acid (PAM), a salicylate with limited ability to cross epithelial barriers.
Structure of polymeric nanoparticles encapsulating a drug–Pamoic acid ion pair by scanning transmission electron microscopy
Natalia Koniuch, Martha Ilett, Sean M. Collins, Nicole Hondow, Andy Brown, Les Hughes, Helen Blade
Heliyon, 2023
A hydrophobic ion-pair between pamoic acid and an active pharmaceutical ingredient (API). … core of PLA and pamoic acid-API material with additional enrichment of the pamoic acid-API …
Syntheses, crystal structures and fluorescent properties of two metal-organic frameworks based on pamoic acid
GH Chen, YP He, SH Zhang, J Zhang
Journal of Solid State Chemistry, 2019
Two three-dimensional (3D) metal organic frameworks (MOFs) with pamoic acid (H 2 pam) ligand have been solvothermally synthesized, namely, [Eu 2 (pam) 3 (H 2 O) 4 ]·3EtOH·2DMF …
Crystalline cepham acid addition salts and processes for their preparation
-
, (2008/06/13)
Novel crystalline cephem acid addition salts and processes for their preparation Compounds of the formula I STR1 in which n is equal to 1 or 2 and m is 0.4-2.6, and where X is the anion of a carboxylic acid, have antibacterial activity.
130-85-8 Process route
- 50-00-0,30525-89-4,61233-19-0
formaldehyd
- 92-70-6
3-Hydroxy-2-naphthoic acid
- 130-85-8
Pamoic acid
Conditions | Yield |
---|---|
With sulfuric acid; In acetic acid; for 10h; Heating;
|
95% |
With sodium hydroxide;
|
|
With sulfuric acid; acetic acid;
|
|
With sodium hydroxide;
|
-
9-(3-Carboxy-2-hydroxy-naphthalen-1-ylmethyl)-2,4-dioxo-4H-1,3-dioxa-2λ5-phospha-anthracen-2-ol anion
- 130-85-8
Pamoic acid
Conditions | Yield |
---|---|
With water; at 40 ℃; Rate constant; var. pHs;
|
130-85-8 Upstream products
-
50-00-0
formaldehyd
-
64-19-7
acetic acid
-
92-70-6
3-Hydroxy-2-naphthoic acid
130-85-8 Downstream products
-
27757-79-5
3-hydroxy-4-phenylazo-[2]naphthoic acid
-
49609-90-7
bis(methyl-2-methoxy-3-naphthoyl)methane
-
217327-71-4
C51H40O6
-
68902-24-9
1-methyl-2-hydroxy-3-naphthoic acid
Relevant Products
-
Thiobenzoic acidCAS NO.: 98-91-9
CAS:98-91-9
-
Octanamide, N-hydroxy-
CAS:7377-03-9
-
Sodium Trimetaphosphate
CAS:7785-84-4